Coupling carbon atoms yields novel molecular architectures

Coupling carbon atoms yields novel molecular architectures

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The Scripps Research Institute (TSRI) invented a new method for joining complex organic molecules could be used to create fabrics, dyes, plastics, pharmaceuticals and other materials, revealed a paper published in the journal Nature. The technique developed by the TSRI team allowed scientists to join two compounds known as olefins to create a new bond between their carbon-atom backbones. Functional groups that would be destroyed by other cross-coupling methods are totally unscathed while using their method. Using a simple iron catalyst, a commercially-available silane and ethanol as a solvent, they performed the reactions in an open flask, eliminating the need to exclude air or moisture. Their reaction created over 60 compounds, 90 percent of which were new chemical entities.